La Crosse County, WI Commercial Property for Sale (83 Real Estate Listings)

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W7665 Sylvester, Holland

$4,975,000

W7665 Sylvester, Holland

160 Acres 10,000 SqFt Commercial MLS® # 1905593

This is a rare opportunity to own an iconic, successful golf course and supper club that combines the beauty of Holmen, WI with a thriving business that has room to grow. Whether you're a pa...

Coldwell Banker Commercial River ValleyLogo

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530 Lang, La Crosse

$2,100,000

530 Lang, La Crosse

0 Acres 13,901 SqFt Commercial MLS® # 1919645

OPPORTUNITIES GALORE, 2 PARCELS/BUILDINGS OFFERED, LOCATED IN THIS HIGH TRAFFIC AREA ON THE NORTHSIDE. THIS IS CURRENTLY A BODY SHOP HOWEVER COULD BE USED FOR MANY THINGS LIKE AN INDOOR STOR...

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Active
207 Causeway, La Crosse

$2,000,000

207 Causeway, La Crosse

2 Acres 30,000 SqFt Commercial MLS® # 1936820

This well-maintained, large commercial property offers exceptional versatility with a combination of shop and office space, ideal for a variety of business needs. Spacious Shop area with 14 ...

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3055 State Road 16, La Crosse

$1,999,999

↓ $300,001

3055 State Road 16, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1902550

SELLER FINANCING available with adequate down payment! Prime opportunity to own highly desired real estate right along Highway 16. Own a turnkey building with a rock solid national tenant th...

eXp Realty LLCLogo

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507 4th 521-529, La Crosse

$1,600,000

507 4th 521-529, La Crosse

1 Acres 5,000 SqFt Commercial MLS® # 1898756

YOUR BUSINESS WILL NOT GET MISSED ON THIS HIGH PROFILE 3/4 ACRE (+/-) DOWNTOWN CORNER IN THRIVING LA CROSSE BUSINESS DISTRICT! PLENTY OF DRIVE BY TRAFFIC/VISIBILITY, CONVENIENT LOCATION FOR...

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651 2nd, Onalaska

$1,500,000

651 2nd, Onalaska

1 Acres 7,492 SqFt Commercial MLS® # 1935016

Don't miss this rare opportunity to own a well-situated 12-room motel right off Interstate I-90 in Wisconsin. Perfectly positioned on a main road with a Wisconsin DOT traffic count of 13,800...

Castle Realty, LLCLogo

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517 Copeland, La Crosse

$1,200,000

517 Copeland, La Crosse

1 Acres 7,240 SqFt Commercial MLS® # 1780187

Choice commercial building for sale with a choice central location. BUSINESS IS NOT FOR SALE! Building features wide open concepts and will adapt itself to a variety of uses. High ceiling...

Cindy Gerke & AssociatesLogo

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4430 Mormon Coulee, La Crosse

$1,050,000

4430 Mormon Coulee, La Crosse

1 Acres 2,320 SqFt Commercial MLS® # 1926604

Commercial property with a 3 Bedroom house and 2 car garage located on the southside of La Crosse near Aldi's / Wendy's and Walmart. Corner lot at the stop lights with 4 curb cuts for ingre...

Gerrard-Hoeschler, REALTORSLogo

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3437-3439 East, La Crosse

$990,000

3437-3439 East, La Crosse

1 Acres 9,730 SqFt Commercial MLS® # 1927801

For Sale or Lease. Professional Office Building located on the South side of La Crosse. Renovations and additions took place in 1994 and 2006, two separate entrances allowing for an additi...

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423 - 425 Main, La Crosse

$750,000

423 - 425 Main, La Crosse

0 Acres 6,000 SqFt Commercial MLS® # 1917713

Great Downtown La Crosse Wisconsin Commercial property for sale! These buildings include a long term business tenant w/ great storefront presence at street level as well as 2 beautiful apart...

United Country Midwest Lifestyle Properties LLCLogo

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2128-2130 State Road 16, La Crosse

$689,000

2128-2130 State Road 16, La Crosse

0 Acres 6,298 SqFt Commercial MLS® # 1933103

A commercial location with visibility to 34,000 vehicles per day!! The light industrial zoning offers the possibility for many businesses in the space. The current clinic has several exam ro...

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103 3rd 227 Main, La Crosse

$685,000

↓ $100,000

103 3rd 227 Main, La Crosse

0 Acres 3,838 SqFt Commercial MLS® # 1906313

FOR SALE OR LEASE! EXCEPTIONAL LOCATION FOR RETAIL OR RESTAURANT W/DRIVE BY & FOOT TRAFFIC EXPOSURE IN HISTORIC DOWNTOWN LA CROSSE: EXPOSURE TO 3RD AND MAIN STREETS W/PLENTY OF BOTH FOOT & C...

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223-227 3rd Street N, La Crosse

$659,999

↓ $15,001

223-227 3rd Street N, La Crosse

0 Acres 5,900 SqFt Commercial MLS® # 1919127

Own a piece of La Crosse history. This well cared for commercial building has three addresses/units and boasts a ton of potential for your business in the historic downtown La Crosse. With ...

Coldwell Banker Commercial River ValleyLogo

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2143 Ward Avenue, La Crosse

$649,000

↓ $16,000

2143 Ward Avenue, La Crosse

0 Acres 8,799 SqFt Commercial MLS® # 1995368

This remarkable commercial property is just what you need! Whether you're looking for an automotive shop, manufacturing business, commercial sales, or endless opportunities, this is for you....

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717 Rose, La Crosse

$629,000

↓ $10,000

717 Rose, La Crosse

0 Acres 3,800 SqFt Commercial MLS® # 1916830

STEP INTO A RARE OPPORTUNITY TO OWN A FULLY RENOVATED AND REMODELED COMMERCIAL PROPERTY THAT IS READY FOR YOUR VISION! CURRENTLY A COMMERCIAL KITCHEN SPACE, BEFORE THAT A BUSTLING BAR AND GR...

Cindy Gerke & AssociatesLogo

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205 Main, Onalaska

$599,900

205 Main, Onalaska

0 Acres 5,136 SqFt Commercial MLS® # 1928617

Turn-Key Restaurant, Catering Business & Real Estate with Prime Main Street location in the heart of Onalaska. An exceptional opportunity that is fully operational and ready for new ownershi...

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591 Lester 581, Onalaska

$565,000

591 Lester 581, Onalaska

1 Acres 2,900 SqFt Commercial MLS® # 1906000

Seller open to seller financing! Great investment opportunity in heart of Onalaska! Own this fully functioning car wash along with the vacant commercial lot next to it! Vacant lot has its ow...

eXp Realty LLCLogo

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427 Main, La Crosse

$550,000

427 Main, La Crosse

0 Acres 3,000 SqFt Commercial MLS® # 1917754

Premier investment opportunity at 427 Main St in the heart of La Crosse, WI! This 1880 mixed-use gem offers a unique blend of character and cash flow. The street-level storefront, leased to ...

United Country Midwest Lifestyle Properties LLCLogo

La Crosse County, WI Real Estate Statistics

Average Price $433K
Lowest Price $0
Highest Price $7M
Total Listings 489
Avg. Days On Market 124
Avg. Price/SQFT $165

Property Types (active listings)


As of October 16, 2025 there are 83 active La Crosse County, WI commercial real estate listings for sale with an average listing price of $308,512. The highest-priced commercial property listing is $4,975,000, while the lowest priced commercial property can be purchased for $0. La Crosse County, WI Commercial properties for sale have an average price of $58 per square foot, based on commercial listings with an average of bedrooms, bathrooms, and 6,459 square feet of living space.

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